The Health Research Council (HRC) has recently announced the recipients of the council’s 2018 career development awards.
Respiratory trainee Dr William Good has been awarded a Clinical Research Training Fellowship and has received funding for his PhD research The role of a sublingual bacterial vaccine in adult bronchiectasis patients. He will be supervised by CM Health respiratory physician Dr Conroy Wong and will start his research in December.
Dr Good graduated from the University of Auckland in 2011. During his house officer years, training at Middlemore and Tauranga hospitals, he developed a passion for respiratory medicine and interest in the complexities and challenges of respiratory disease. He has been involved in previous research projects at the University of Auckland, clinical trials at Middlemore Clinical Trials unit and audit projects while working at Middlemore Hospital and Auckland City Hospital.
“I am extremely excited to be undertaking a PhD through the University of Auckland with the support of Ko Awatea at Counties Manukau Health,” he says.
The research – Dr. Good’s PhD will investigate the use of a novel oral bacterial vaccine in patients with bronchiectasis. Bronchiectasis is a chronic, debilitating disease characterised by productive cough, airway inflammation, and repeated respiratory infections. It disproportionately affects Māori and Pacific peoples in New Zealand. The vaccine is delivered under the tongue leading to direct absorption and bypasses the problem of inactivation in the gut. It offers a potentially simple and non-antibiotic treatment option for the prevention of infective exacerbations in patients with bronchiectasis. He will run a feasibility, randomised, placebo-controlled trial evaluating the benefit of Bactek-R, a sublingual vaccine. The potential benefits include fewer exacerbations, improved quality of life and reduced healthcare costs. The study will also investigate the lung microbiome, analysing bacteria found in the airways of bronchiectasis patients.